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ChemInform Abstract: Synthesis and in vitro Cytotoxicity of cis-Dichloro((2S,3R,4S)-2- aminomethyl-3,4-(O-isopropylidene)dihydroxy- or -3,4- dihydroxypyrrolidine)platinum(II).

โœ Scribed by D.-K. KIM; Y.-W. KIM; H.-T. KIM; K. H. KIM


Book ID
112034720
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
27
Category
Article
ISSN
0931-7597

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Synthesis and in vitro cytotoxicity of c
โœ Dae-Kee Kim; Jongsik Gam; Hun-Taek Kim; Key H. Kim ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 264 KB

The synthesis and in vitro cytotoxicity of cis-(glycolato-O,O')[2-substituted-(4R,5R)-4,5bis(aminomethyl)-l,3-dioxolane]platinum(II) are described. Among them, cis-(glycolato-O,O')[(4R,5R)-4,5-bis(aminomethyl)-2,2-diethyl-l,3-dioxolane]platinum(II) (26) was found to be almost equally cytotoxic to ci