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ChemInform Abstract: Synthesis and Cytotoxicity of Phenylvinyl Derivatives of 4,6,6-Trimethyl-2-oxo-1,2,5,6-tetrahydropyridine-3-carbonitrile.

โœ Scribed by E. Lukevics; D. Jansone; L. Leite; J. Popelis; G. Andreeva; I. Shestakova; I. Domracheva; V. Bridane; I. Kanepe

Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
41
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Ethylcrotonates in
ChemInform Abstract: Ethylcrotonates in the Synthesis of 4,4-Disubstituted 3,5-Dicyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates.
โœ V. D. DYACHENKO; A. A. NIKISHIN; V. P. LITVINOV ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 2 views

Ethylcrotonates in the Synthesis of 4,4-Disubstituted 3,5-Dicyano-6oxo-1,4,5,6-tetrahydropyridine-2-thiolates. -Michael addition of ethyl crotonate (I) to cyanothioacetamide (II) in the presence of N-methylmorpholine and subsequent in situ cyclization affords the title tetrahydropyridinethiolates as