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ChemInform Abstract: Synthesis and Cytotoxic Evaluation of Some Carbohydrazones and Thiocarbohydrazones of Various Unsaturated Ketones and Related Mannich Bases.

โœ Scribed by J. R. DIMMOCK; P. KUMAR; T. M. ALLEN; G. Y. KAO; S. HALLERAN; J. BALZARINI; E. DE CLERCQ


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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Synthesis and Reactivity of Some Mannich Bases. Part 7. Synthesis of 3-(2-Dialkylaminoethyl)-1,2-benzisoxazoles. -Acetylation of the oximes (I) and direct basic treatment of the resulting Mannich base oxime acetates (III) yields the 1,2-benzisoxazoles (IV), required as pharmaceutical agents. -(COMA