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ChemInform Abstract: Synthesis and Cytotoxic Activity of Heterocyclization Products of 1,1-Dicyano-2-hetaryl-2-trifluoromethylethylenes.

✍ Scribed by Yu. E. Pavlova; A. F. Shidlovskii; D. B. Gusev; A. S. Peregudov; Yu. N. Bulychev; N. D. Chkanikov

Publisher
John Wiley and Sons
Year
2011
Weight
39 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

A variety of novel Fluorinated N‐heterocycles is synthesized by heterocyclization reactions of the title olefins (II) with nitrogen compounds.

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Synthesis and Cytotoxic Activity of 1-Alkoxy-and 1-Amino-2hydroxy-1,2-dihydroacronycine Derivatives. -In order to get more information about the structure-activity relationships, a novel series of acronycine derivatives such as (I) and (II) (16 examples) are synthesized. The most active substance (