ChemInform Abstract: Synthesis and Biological Evaluation of Butanoate, Retinoate, and Bis(2,2,2-trichloroethyl)phosphate Derivatives of 5-Fluoro-2′-deoxyuridine and 2′,5-Difluoro-2′-deoxyuridine as Potential Dual Action Anticancer Prodrugs.
✍ Scribed by Zuping Xia; Leonard I. Wiebe; Gerald G. Miller; Edward E. Knaus
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 26 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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Synthesis and Biological Activity of Bis(pivaloyloxymethyl) Ester of 2'-Azido-2'-deoxyuridine 5'-Monophosphate. -The title compound (III) which is the membrane-permeable prodrug of the phosphate (I), is evaluated with positive results for inhibition of cell growth with 60 tumor cell lines.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v