✦ LIBER ✦

ChemInform Abstract: Synthesis and Biological Evaluation of 1-[2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]-4-ethynylimidazole. A Novel and Highly Potent Antiinflammatory and Cytoprotective Agent.

✍ Scribed by Tadashi Honda; Albena T. Dinkova-Kostava; Emilie David; Eric M. Padegimas; Chitra Sundararajan; Melean Visnick; Ron Bumeister; W. Christian Wigley

Publisher: John Wiley and Sons
Year: 2011
Weight: 24 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201134209

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A small series of new N‐acyl(acetylenic)imidazole analogues (I) is synthesized and evaluated for their anti‐inflammatory and cytoprotective activity.

📜 SIMILAR VOLUMES

ChemInform Abstract: 2-Cyano-3,10-dioxoo

ChemInform Abstract: 2-Cyano-3,10-dioxooleana-1,9(11)-dien-28-oic Acid Anhydride. A Novel and Highly Potent Antiinflammatory and Cytoprotective Agent.

✍ Tadashi Honda; Eric M. Padegimas; Emilie David; Chitra Sundararajan; Karen T. Li 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 18 KB

## Abstract Title compound (I) is easily synthesized as first example of an oleane triterpenoid anhydride.

ChemInform Abstract: A Novel Dicyanotrit

ChemInform Abstract: A Novel Dicyanotriterpenoid, 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, Active at Picomolar Concentrations for Inhibition of Nitric Oxide Production

✍ Tadashi Honda; Yukiko Honda; Frank G. Favaloro Jr.; Gordon W. Gribble; Nanjoo Su 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 27 KB 👁 1 views

ChemInform Abstract: Design and Synthesi

ChemInform Abstract: Design and Synthesis of 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid, a Novel and Highly Active Inhibitor of Nitric Oxide Production in Mouse Macrophages.

✍ T. HONDA; B. V. ROUNDS; G. W. GRIBBLE; N. SUH; Y. WANG; M. B. SPORN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

ChemInform Abstract: Design, Synthesis a

ChemInform Abstract: Design, Synthesis and Biological Evaluation of Novel 2-[(2,4-Diaryl-3-azabicyclo [3.3.1]nonan-9-ylidene)hydrazone]-1,3-thiazolidin-4-ones as a New Class of Antimicrobial Agents.

✍ R. Ramachandran; M. Rani; S. Kabilan 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views