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ChemInform Abstract: Synthesis and Biological Activity of Some 4-Benzyl-1(2H)-phthalazinone Derivatives.

✍ Scribed by EL-S. H. EL-TAMATY; M. E. ABDEL-FATTAH; I. M. EL-DEEN

Book ID
112042067
Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
27
Category
Article
ISSN
0931-7597

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## Abstract Microwave irradiation of 1(2__H__)‐phthalazinone with benzyl halides and potassium carbonate in dimethyl‐formamide afforded 2‐benzyl‐1(2__H__)phthalazinones in modest yields. These products were tested in mice and rats in maximal electroshock and pentylenetetrazole seizure models for an