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ChemInform Abstract: Synthesis and Biological Activity of Sarcodictyins.

โœ Scribed by K. C. NICOLAOU; S. KIM; J. PFEFFERKORN; J. XU; T. OHSHIMA; S. HOSOKAWA; D. VOURLOUMIS; T. LI


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
29
Category
Article
ISSN
0931-7597

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A new class of potential antitumor agents with a taxol-like mechanism of action is presented by the sarcodictyins 1. Modification of the reported syntheses of sarcodictyins permitted the preparation of additional derivatives, the biological properties of which are highly dependent upon the structure