𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Synthesis and Antitumor Evaluation of New Thiazolo(5,4-b)quinoline Derivatives.

✍ Scribed by C. ALVAREZ-IBARRA; R. FERNANDEZ-GRANDA; M. L. QUIROGA; A. CARBONELL; F. CARDENAS; E. GIRALT

Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
28
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

Synthesis and Antitumor Evaluation of New Thiazolo(5,4-b)quinoline Derivatives.

-A new synthetic pathway to title compounds such as (II), (III), (IV), ( VI), (VIII), and (XI) uses thiazoles (I) as starting compounds. Cyclocondensation of (I) as well as of (X) is accomplished with the nonoxidative system POCl3/PPA, that can be used at high temperature. Among eight derivatives, compound (VI) exhibits significant cytotoxicity against mouse leukemic P-388, human lung carcinoma A-549, and human colon tumor HT-29 cell growth in vitro.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Synthesis and Antim
ChemInform Abstract: Synthesis and Antimicrobial Evaluation of Some New Thiazolo[4,5-d]pyrimidines.
✍ Ayla Balkan; Huesne Urgun; Meral Oezalp πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v