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ChemInform Abstract: Synthesis and Antitumor Activity of Water-Soluble Duocarmycin B1 Prodrugs.

✍ Scribed by Akira Asai; Satoru Nagamura; Eiji Kobayashi; Katsushige Gomi; Hiromitsu Saito

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
31
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.

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## Synthesis and Antitumor Activity of 4-Phenyl-1arylsulfonylimidazolidinones. -The novel title compounds (VII) and (VIII) display highly potent and broad cytotoxicities. The most potent derivative (VIII) exhibits much more potent cytotoxicities than doxorubicin and highly effective antitumor act