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ChemInform Abstract: Synthesis and Antitumor Activity of Novel Pyrazolylenaminone and Bis(pyrazolyl)ketones via Hydrazonoyl Halides.

✍ Scribed by Ahmad S. Shawali; Sherif M. Sherif; Mahmoud M. El-Merzabani; Manal A. A. Darwish

Publisher
John Wiley and Sons
Year
2009
Weight
24 KB
Volume
40
Category
Article
ISSN
0931-7597

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Synthesis and antitumor activity of nove
Synthesis and antitumor activity of novel pyrazolylenaminone and bis(pyrazolyl)ketones via hydrazonoyl halides
✍ Ahmad S. Shawali; Sherif M. Sherif; Mahmoud M. El-Merzabani; Manal A. A. Darwish 📂 Article 📅 2009 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 103 KB

## Abstract magnified image 3‐Acetyl‐4‐benzoyl‐1,5‐diphenylpyrazole reacts with DMF‐DMA to give the novel enaminone **2**. The reaction of the latter with various hydrazonoyl halides afforded regioselectively the respective substituted (3‐pyrazolyl)(4‐pyrazolyl)ketones **4** in good over all yield