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ChemInform Abstract: Synthesis and Antiinflammatory Activity of 4,6-Diphenyl-2-pyrimidinecarboxylic Acid Amides.

✍ Scribed by G. Myakushkene; E. Ubrenaite; P. Gaibyalis; P. Vainilavichyus

Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

Synthesis and Antiinflammatory Activity of 4,6-Diphenyl-2pyrimidinecarboxylic Acid Amides.

-Several title pyrimidinecarboxylic acid amides (III) (17 examples) are prepared by amidation of the corresponding acid chlorides (I). The methoxy-and p-halogenoaryl derivatives (IIIc) -(IIIe) possess the best antiinflammatory activity comparable to acetylsalicylic acid.

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v