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ChemInform Abstract: Synthesis and Antihypertensive Activity of Novel 1-(4-Benzyl-1- phthalazinyl)pyrazolo(3,4-d)pyrimidines.

✍ Scribed by S. A. EL-FEKY; Z. K. ABD EL-SAMII

Book ID: 112040767
Publisher: John Wiley and Sons
Year: 2010
Weight: 32 KB
Volume: 27
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199648169

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ChemInform Abstract: Synthesis of 4-Substituted 1-((2,3-Dihydroxy-1-propoxy)methyl)-1H- pyrazolo(3,4-d)pyrimidines.

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Synthesis of 4-Substituted 1-((2,3-Dihydroxy-1-propoxy)methyl)-1Hpyrazolo (3,4-d)pyrimidines. -The regioselective synthesis of a series of acyclonucleosides of pyrazolopyrimidines (cf. (IV), (V), (VII), (IX)) is described. The obtained compounds are evaluated for their cytotoxicity and anti-HIV act