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ChemInform Abstract: Synthesis and Antidiuretic Activities of Novel Glycoconjugates of Arginine—Vasopressin.

✍ Scribed by Hiroshi Susaki; Kokichi Suzuki; Masahiro Ikeda; Harutami Yamada; Hiroshi K. Watanabe

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
30
Category
Article
ISSN
0931-7597

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We report the solid phase synthesis and vasodepressor potencies of the novel hypotensive peptide [1(-i-mercapto-i,i-pentamethylene propionic acid)-2-O-ethyl-D-tyrosine, 3-arginine, 4-valine] arginine vasopressin, d(CH 2 ) 5 [D-Tyr(Et) 2 , Arg 3 , Val 4 ]AVP (A), its related Lys 3 (B), Tyr-NH 2 9 (C)