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ChemInform Abstract: Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease: Structure-Based Design, Synthesis, and Biological Evaluation.

✍ Scribed by Siegfried H. Reich; et al. et al.

Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
31
Category
Article
ISSN
0931-7597

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Design and Synthesis of Monocyclic Ξ²-Lactams as Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. -Starting from monocyclic Ξ²-lactams novel human cytomegalovirus protease inhibitors, e.g. (III), (VII),and (VIII), are developed. The most potent one among them is the derivative (VII) with