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ChemInform Abstract: Substituent Effects on the Regioselectivity of Enzymatic Acylation of 6-O-Alkylglycopyranosides Using Pseudomonas cepacia Lipase.

โœ Scribed by D. A. MACMANUS; E. N. VULFSON


Book ID
112030311
Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
27
Category
Article
ISSN
0931-7597

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Substituent effects on the regioselectiv
โœ David A. MacManus; Evgeny N. Vulfson ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 730 KB

The regioselectivity of acylation of a range of 6-O-protected glycosides using Pseudomonas cepacia lipase in vinyl acetate was investigated. In general, cY-glycosides were acylated at the O-2 position and P-glycosides were acylated at the O-3 position. The effects of varying the size/hydrophobicity