ChemInform Abstract: Studies Towards a Synthesis of Epothilone A: Stereocontrolled Assembly of the Acyl Region and Models for Macrocyclization.
β Scribed by P. BERTINATO; E. J. SORENSEN; D. MENG; S. J. DANISHEFSKY
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 39 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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Synthesis Studies Directed Towards Epothilone A: Enantioselective Synthesis of a C 7 -C 15 Carboxaldehyde Segment. -Based on the diastereoselective alkylation of Oppolzer's sultam (III) with the iodide (II), the desired (S)-product (IV) is prepared and readily transformed to the C7-C15 segment of e
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