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ChemInform Abstract: Studies of Benzoxazines. Part 16. Synthesis and Reactivity of 2,4-Substituted 4H-3,1-Benzoxazines.

✍ Scribed by E. V. Gromachevskaya; V. G. Kul'nevich; T. P. Kosulina

Book ID: 112048672
Publisher: John Wiley and Sons
Year: 2012
Weight: 40 KB
Volume: 43
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201232180

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Various 3-substituted-4H-1,4-benzoxazines were prepared in good yields by lithiation-electrophilic substitution of the 4-Boc-4H-l,4-benzoxazine. The synthesis of this carbamic derivative, in four steps from 2aminophenol, was described.