Analogues of the aminoacyl tRNA synthetase inhibitor, indolmycin, have been synthesised in which the side chain methyl group is replaced by a wide range of substituents. Their antibacterial and enzyme inhibitory potency is related to steric properties and conformational preferences.
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ChemInform Abstract: Structure-Activity Dependency of New Bacterial Tryptophanyl tRNA Synthetase Inhibitors.
β Scribed by D. R. WITTY; G. WALKER; J. H. BATESON; P. J. O'HANLON; R. CASSELS
- Book ID
- 112039023
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
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