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ChemInform Abstract: Stereospecific Synthesis of (2S,4R)-(5,5,5-D3)Leucine.

โœ Scribed by R. A. AUGUST; J. A. KHAN; C. M. MOODY; D. W. YOUNG


Book ID
112035091
Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
27
Category
Article
ISSN
0931-7597

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Stereoselective synthesis of (2S,3S,4R,5
โœ Makoto Oba; Tsutomu Terauchi; Jun Hashimoto; Tomohiro Tanaka; Kozaburo Nishiyama ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 227 KB

A catalytic deuteration of protected 3,4-dehydro-L-proline using RuCI2(PPh3) 3 followed by RuO~-oxidation gave a 3,4-dideuterated L-pyroglutamic acid derivative which is considered to be a promising precursor for various deuterated amino acids. The present study demonstrates a stereoselective reduct