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ChemInform Abstract: Stereospecific Syntheses of (S)-(+)-Parasorbic Acid: (S)-(+)-5,6-Dihydro-6-methyl-2H-pyran-2-one

✍ Scribed by Radia Mahboub


Publisher
John Wiley and Sons
Year
2009
Weight
11 KB
Volume
40
Category
Article
ISSN
0931-7597

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The Stereoselective Total Synthesis of (
✍ Jhillu Singh Yadav; Dandekar Chandrakanth; Yerragorla Gopala Rao; Kontham Ravind 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 German ⚖ 180 KB

## Abstract The stereoselective total synthesis of an antiproliferative and antifungal __α__‐pyrone natural product (6__S__)‐5,6‐dihydro‐6‐[(2__R__)‐2‐hydroxy‐6‐phenylhexyl]‐2__H__‐pyran‐2‐one is described. The key steps involved are the __Prins__ cyclization, __Mitsunobu__ reaction, and ring‐closi