✦ LIBER ✦

ChemInform Abstract: Stereoselective Synthesis of Enantiomerically Pure Isoxazolidine-Fused δ-Lactams.

✍ Scribed by Ugo Chiacchio; Antonino Corsaro; Anna Piperno; Antonio Rescifina; Giovanni Romeo; Roberto Romeo

Publisher: John Wiley and Sons
Year: 2010
Weight: 35 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199926151

No coin nor oath required. For personal study only.

✦ Synopsis

Stereoselective Synthesis of Enantiomerically Pure Isoxazolidine-Fused δ-Lactams.

-Starting from homochiral amido aldehydes (V) and (XIII) which possess a chiral center in α-position with respect to nitrone functionality, the homochiral S-lactams (VII) and (XV) containing four contiguous chiral centers are synthesized. The selective ring cleavage of the isoxazolidine nucleus in (VIIa) constitutes a new easy entry to the stereoselective formation of piperidines and indolizidines with high diastereoselection and optical purity. -

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Enanti

ChemInform Abstract: Synthesis of Enantiomerically Pure Bicylic Lactams.

✍ Nicole Diedrichs; Bernhard Westermann 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

ChemInform Abstract: Stereoselective Syn

ChemInform Abstract: Stereoselective Synthesis of Enantiomerically Pure Drugs

✍ Maurizio Benaglia; Mauro Cinquini; Franco Cozzi 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 23 KB 👁 1 views

ChemInform Abstract: Synthesis of Enanti

ChemInform Abstract: Synthesis of Enantiomerically Pure Nucleosides

✍ B. L. BRAY; M. D. GOODYEAR; J. J. PARTRIDGE; D. J. TAPOLCZAY 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 23 KB 👁 2 views

ChemInform Abstract: Synthesis of Enanti

ChemInform Abstract: Synthesis of Enantiomerically Pure Cyclohexylglycine

✍ Adriaan J. Minnaard; Wilhelmus H. J. Boesten; Hubertus J. M. Zeegers 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 25 KB 👁 2 views

ChemInform Abstract: Stereoselective Tot

ChemInform Abstract: Stereoselective Total Synthesis of Enantiomerically Pure 1-Trifluoromethyl Tetrahydroisoquinoline Alkaloids.

✍ P. BRAVO; M. CRUCIANELLI; A. FARINA; S. V. MEILLE; A. VOLONTERIO; M. ZANDA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

ChemInform Abstract: Stereoselective Syn

ChemInform Abstract: Stereoselective Synthesis of Fluorinated Isoxazolidines and 2,3-Dihydroisoxazoles: A Cycloadditive Route to Enantiomerically Pure Amino Fluoro Alcohols.

✍ Luca Bruche; Alberto Arnone; Pierfrancesco Bravo; Walter Panzeri; Cristina Pesen 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views