Stereoselective Synthesis of a 2,3-Disubstituted 5-Pyrrolidinone Derivative of Quinazolin-4(3H)-one. -Thermal acylation of the quinazolinone (III) with ethyl acetoacetate and subsequent thermal cyclization of the intermediate acetoacetamide results in selective formation of the title compound (V),
โฆ LIBER โฆ
ChemInform Abstract: Stereoselective Synthesis of 2,3-Disubstituted Glutamic Acid Derivatives by Conjugate Addition to 3,4-Didehydropyroglutamates.
โ Scribed by G. GUILLENA; B. MANCHENO; C. NAJERA; J. EZQUERRA; C. PEDREGAL
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 37 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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