𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Stereoselective Syntheses of (+)-Rhopaloic Acid A and (-)-ent- and (.+-.)-rac-Rhopaloic Acid A.

✍ Scribed by R. TAKAGI; A. SASAOKA; H. NISHITANI; S. KOJIMA; Y. HIRAGA; K. OHKATA

Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
29
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

Stereoselective Syntheses of (+)-Rhopaloic Acid A and (-)-ent-and (Β±)-rac-Rhopaloic Acid A. -Total syntheses of natural rhopaloic acid (XIII), its enantiomer and racemate via successive homologation of farnesol (I) and cyclization to form the tetrahydropyran ring are described. The asymmetric synthesis is achieved by way of the Evans' asymmetric alkylation of mixed anhydride derived from carboxylic acid (II) and pivaloyl chloride using 4-benzyloxazolidinones as chiral auxiliaries. -(TAKAGI, R.; SASAOKA, A.;

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Asymmetric Synthesi
ChemInform Abstract: Asymmetric Synthesis of Rhopaloic Acid A Analogues and Their Biological Properties.
✍ Hiroko Nishitani; Asami Sasaoka; Munetaka Tokumasu; Katsuo Ohkata πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 29 KB

Asymmetric Synthesis of Rhopaloic Acid A Analogues and Their Biological Properties. -In order to study structure-activity relationships of cytotoxic rhopaloic acid, related analogues such as (X) are synthesized. The routes are based on asymmetric alkylation of a chiral oxazolidine (I) and construct

ChemInform Abstract: A [3 + 3] Anellatio
ChemInform Abstract: A [3 + 3] Anellation Approach to (+)-Rhopaloic Acid B.
✍ Julien C. R. Brioche; Katharine M. Goodenough; David J. Whatrup; Joseph P. A. Ha πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons βš– 47 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

ChemInform Abstract: Investigation of an
ChemInform Abstract: Investigation of an Organomagnesium-Based [3 + 3] Anellation to Pyrans and Its Application in the Synthesis of Rhopaloic Acid A.
✍ Julien C. R. Brioche; Katharine M. Goodenough; David J. Whatrup; Joseph P. A. Ha πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons βš– 51 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v