Stereoselective Amination of 5-Substitut
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Marko S'kof; Jurij Svete; Matej Kmetič; Simona Golič-Grdadolnik; Branko Stanovnik
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Article
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1999
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John Wiley and Sons
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English
⚖ 249 KB
5-Substituted (S)-tetrahydrofuran-2-ones (1a,b) and (S)-catalytic hydrogenation, into the corresponding 5-substituted (3S,5S)-3-acetylaminotetrahydrofuran-2-ones (4a,b) and pyrrolidin-2-ones (1c,d) were transformed in three steps, by treatment with tert-butoxybis(dimethylamino)methane (Bre-(3S,5S)-3