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ChemInform Abstract: Short Synthetic Route to Retinoids Through Dialkylation of 3-Methyl-3- sulfolene.

โœ Scribed by T. SUBRAMANIAN; R. PADMAKUMAR; S. V. BHAT

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
28
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Short Synthetic Route to Retinoids Through Dialkylation of 3-Methyl-3-sulfolene.

-Sequential alkylation of 3-methyl-3-sulfolene (I) with bromomethyl ether (II) followed by aldehyde (IV) provides a short and efficient route to retinol methyl ether (VII). An analogous sequence allows the preparation of the pentaene (X). -(SUBRAMANIAN, T.; PADMAKUMAR,

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