ChemInform Abstract: A Short, Multigram Synthetic Route to Methyl 2-Amino-4-methyl-3-thiophenecarboxylate as a Precursor for Preparation of New Biologically Active Derivatives and Novel Materials.

✍ Scribed by R. PAVLOVICOVA; J. MINARIKOVA; D. HUDECOVA; D. VEGH

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 35 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199827128

✦ Synopsis

thiophenecarboxylate (III) and its conversion into novel ethylenic thiophenes (IX) is described. The antimicrobial activity of the prepared compounds is evaluated. Derivative (Va), the most active compound, shows remarkable antimicrobial activity on filamentous fungi.