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ChemInform Abstract: Sequential Sonogashira/Carbopalladative Cyclization/Suzuki Reactions Catalyzed by a Single Palladium Source by Using Protected Homopropargyl Alcohol.

โœ Scribed by Xin Wang; Lingyan Liu; Weixing Chang; Jing Li


Publisher
John Wiley and Sons
Year
2011
Weight
41 KB
Volume
42
Category
Article
ISSN
0931-7597

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โœฆ Synopsis


Abstract

Protected homopropargyl alcohol (I) is converted into indene derivatives by a new cascade sequence including Sonogashira coupling with aryl iodides (II) or aryl bromides (V), carbopalladative cyclization and Suzuki coupling with aryl boronic acids (III).


๐Ÿ“œ SIMILAR VOLUMES


Sequential Sonogashira/Carbopalladative
โœ Xin Wang; Lingyan Liu; Weixing Chang; Jing Li ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 157 KB

## Abstract A novel cascade combination reaction catalyzed by a single palladium source for the synthesis of various indene derivatives is reported. The approach involved sequential Sonogashira/carbopalladative cyclization/Suzuki coupling reactions by using three readily available components, such