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ChemInform Abstract: Sequencing Single DNA Molecules in Real Time

โœ Scribed by Jenny Ibach; Susanne Brakmann


Publisher
John Wiley and Sons
Year
2009
Weight
11 KB
Volume
40
Category
Article
ISSN
0931-7597

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Sequencing Single DNA Molecules in Real
โœ Jenny Ibach; Susanne Brakmann ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 652 KB

## Abstract **One's enough**: The direct observation of a DNAโ€polymeraseโ€based โ€œsequencing engineโ€ using singleโ€molecule detection recently allowed singleโ€molecule sequencing by synthesis in real time. Nucleotides with a fluorescent marker at the 5โ€ฒโ€phosphate unit and zeroโ€mode waveguides are cruci