Sequencing Single DNA Molecules in Real
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Jenny Ibach; Susanne Brakmann
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Article
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2009
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John Wiley and Sons
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English
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## Abstract **One's enough**: The direct observation of a DNAโpolymeraseโbased โsequencing engineโ using singleโmolecule detection recently allowed singleโmolecule sequencing by synthesis in real time. Nucleotides with a fluorescent marker at the 5โฒโphosphate unit and zeroโmode waveguides are cruci