ChemInform Abstract: Selective Reactions of 1,1-Cycloalkanedicarboxylic Acids with SF4. A Route to 1,1-Bis(trifluoromethyl)cycloalkanes, 1-Fluoroformyl-1-(trifluoromethyl)cycloalkanes and 1-(Trifluoromethyl)-1-cycloalkanecarboxylic Acids.
β Scribed by Wojciech Dmowski; Adam Wolniewicz
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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Reaction of Ethyl 4,4,4-Trifluoroacetoacetate Enolate with 3-Bromo-1,1, 1-trifluoroacetone: Synthesis of 2,4-Bis(trifluoromethyl)furan. -The title reaction follows competing courses such as C-acylation, O-alkylation and di-O-alkylation which result in the formation of two major products (III) and (I