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ChemInform Abstract: Selective Generation of Quaternary All-Carbon-Centers Through Heck-Cyclizations: Synthesis of Mesembrane.

✍ Scribed by Johannes E. M. N. Klein; Kimberly Geoghegan; Nicolas Meral; Paul Evans


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
41
Category
Article
ISSN
0931-7597

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ChemInform Abstract: The Synthesis of Qu
✍ G. MAJETICH; J. FANG πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 26 KB πŸ‘ 1 views

The Synthesis of Quaternary Carbon Centers Through Cyclialkylations. -Treatment of the conjugated dienone (I) with Lewis acid at low temperature results in Diels-Alder reaction including the arene moiety to yield a hydrophenanthrene (II) with a newly created quaternary carbon. At higher temperature