A strategy based upon a "cascade" of three consecutive cycloaddition reactions [3+2], [2+2+2] and [4+2] allowed a stereoselective and straightforward access to the phyllocladane basic skeleton in eight high yield steps starting from 1,5-hexadiyne.
β¦ LIBER β¦
ChemInform Abstract: Reversal of the Diastereoselectivity in a Sequence of Cycloaddition Reactions: (2 + 2 + 2), Ene Type, (4 + 2). A Totally Stereoselective Access to the Basic Skeleton of the Kaurane Family.
β Scribed by P. CRUCIANI; C. AUBERT; M. MALACRIA
- Book ID
- 112031597
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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