ChemInform Abstract: Cyano Diels—Alder and Cyano Ene Reactions. Applications in a Formal [2 + 2 + 2] Cycloaddition Strategy for the Synthesis of Pyridines.
✍ Scribed by Takeo Sakai; Rick L. Danheiser
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 60 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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A New [4 + 2] Cycloaddition Strategy for the Synthesis of N-Acyl-7-azabicyclo[2.2.1]heptan-2-ones: A Formal Synthesis of (±)-Epibatidine. -The title compound (VIII), an intermediate for the preparation of (±)-epibatidine, is prepared via Diels-Alder reaction of allenes with N-acylated pyrrole (II)