ChemInform Abstract: Regiospecific Synthesis of a New Chiral N-Substituted Pyrazole Using a Sesquiterpene Hydrocarbon.
β Scribed by A. Auhmani; E. Kossareva; M. Reglier; M. Pierrot; A. Benharref
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Reaction of spirocyclopropanepyrazole derivative (I) with Ξ±βchloro esters (III) in the presence of a NaI/K~2~CO~3~ system results in cyclopropane ring opening and subsequent Cβ or Nβsubstitution to furnish dihydropyridazines (IV) and Nβsubstituted dihydropyrazoles (V).
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