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ChemInform Abstract: Reductive Cleavage of Potential Cholinomimetics Thiadiazolidinones: A New Family of Spiro Compounds.

✍ Scribed by Ana Martinez; Diana Alonso; Ana Castro; Enrique Gutierrez-Puebla; Josep-Eladi Banos; Albert Badia

Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
31
Category
Article
ISSN
0931-7597

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Reductive Cleavage of Potential Cholinom
Reductive Cleavage of Potential Cholinomimetics Thiadiazolidinones: A New Family of Spiro Compounds
✍ Ana Martinez; Diana Alonso; Ana Castro; Enrique Gutierrez-Puebla; Josep-EladΓ­ Ba πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 283 KB

The design, synthesis and evaluation of a series of 1,2,4-thiadiazolidinones with potential muscarinic receptor binding properties has been performed. During the synthesis of the target compounds, we observed an interesting reductive cleavage of the thiadiazolidinone system which leads to the format