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ChemInform Abstract: Reductive Amination of Carboxylic Acids and [11C]Magnesium Halide Carboxylates.

โœ Scribed by Cecile Perrio-Huard; Catherine Aubert; Marie-Claire Lasne


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: One-Pot Reduction o
โœ J. M. HERBERT; A. T. HEWSON; J. E. PEACE ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 2 views

One-Pot Reduction of Carboxylic Acids via O-Acylisoureas. -A simple one-pot conversion of carboxylic acids to primary alcohols is reported. Functional groups like nitro, amides, and carbamates as well as double bonds are tolerated. Aromatic carboxylic acids like (III) give a mixture of the alcohol