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ChemInform Abstract: Reduction of 2-Acylaziridines by Samarium(II) Iodide. An Efficient and Regioselective Route to β-Amino Ketones and Esters.

✍ Scribed by G. A. MOLANDER; P. J. STENGEL


Book ID
112028584
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
27
Category
Article
ISSN
0931-7597

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o!,P-Epoxy esters were rapidly reduced at room temperature to yield P-hydroxy esters with retention of the configurations at the P-carbon atoms by using Sm12-THF-HMPA system in the presence of N,N-dimethylaminoethanol (DMAE). to the synthesis of vinylogous &'-hydroxy esters. The conditions were succ