## Abstract Heating the title quinoxalinones such as (I) and (III) with sulfur in DMF results in a rearrangement accompanied by elimination of the acyl groups.
ChemInform Abstract: Rearrangement of 2-(2-Aryl-2-oxoethyl)-1,2-dihydropyrido[2,3-b]pyrazin-3(4H)-ones (I).
β Scribed by N. N. Kolos; L. Yu. Kovalenko
- Publisher
- John Wiley and Sons
- Year
- 2008
- Weight
- 15 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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## Abstract In an attempt to develop potent antitumor agents, a series of novel 2βhydrazonylpyrido[2,3β__b__]pyrazinβ3(4__H__)βone derivatives were designed and synthesized. All the prepared compounds were screened for their cytotoxic activities against A549, MDAβMBβ231 and HTβ29 cell lines __in vi