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ChemInform Abstract: Rearrangement of 2-(2-Aryl-2-oxoethyl)-1,2-dihydropyrido[2,3-b]pyrazin-3(4H)-ones (I).

✍ Scribed by N. N. Kolos; L. Yu. Kovalenko


Publisher
John Wiley and Sons
Year
2008
Weight
15 KB
Volume
39
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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## Abstract In an attempt to develop potent antitumor agents, a series of novel 2‐hydrazonylpyrido[2,3‐__b__]pyrazin‐3(4__H__)‐one derivatives were designed and synthesized. All the prepared compounds were screened for their cytotoxic activities against A549, MDA‐MB‐231 and HT‐29 cell lines __in vi