ChemInform Abstract: Synthesis Toward Ep
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Hyo Won Lee; Yong Deog Hong; Ihl-Young Choi Lee
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Article
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2010
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John Wiley and Sons
⚖ 34 KB
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Synthesis Toward Epothilone A: Coupling Reaction Between the Sulfone of C 1 -C 10 and the Allylic Bromide of C 11 -C 21 . -The synthesis of macrolide (XII), a precursor of epothilone A, involving the coupling between allylic bromide (IX) and sulfone (X) as the key step is reported. -