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ChemInform Abstract: Radical Substituent Effects of α-Fluorine and α-Trifluoromethyl Groups.

✍ Scribed by X.-M. ZHANG


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.


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New Efficient Syntheses of α-Difluoromethyl-and α-Trifluoromethylornithine. -Ornithines (V), possessing a broad spectrum of biological activities including anticancer activity, are prepared in three steps. The key step is the regioselective alkylation of the imine (I) with the acetylide (II) in exc