Radical Cyclization/β-Elimination Tandem
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Emmanuel Lacôte; Bénédicte Delouvrié; Louis Fensterbank; Max Malacria
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Article
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1998
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John Wiley and Sons
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English
⚖ 109 KB
Alkylidene-substituted cyclopentane derivatives are formed in high enantiomeric purity by the reaction shown below. A highly diastereoselective radical cyclization is followed by elimination of a β-sulfinyl radical. Interestingly, the addition of the Lewis acid methylaluminum bis(2,6-di-tert-butyl-4