ChemInform Abstract: Radical Cyclization of N-Allyl-2-halo Amide in Water.
โ Scribed by Katsuyu Wakabayashi; Hideki Yorimitsu; Hiroshi Shinokubo; Koichiro Oshima
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 32 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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Total Synthesis of (-)-ฮณ-Lycorane Using Diastereoselective 5-endotrig Radical Cyclization of N-Vinylic ฮฑ-Halo Amides. -Radical cyclization of the acetamides (IV) proceeds with only moderate diastereoselectivity. Major product (Va) is converted to the title alkaloid (XI). -
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