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ChemInform Abstract: Protein Mimicry: A New Dimension for Peptides as Lead Compounds?

โœ Scribed by U. REINEKE; J. SCHNEIDER-MERGENER


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
29
Category
Article
ISSN
0931-7597

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Protein Mimicry: A New Dimension for Pep
โœ Ulrich Reineke; Jens Schneider-Mergener ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 116 KB ๐Ÿ‘ 1 views

A short peptide as mimic for the hemopoietic growth factor erythropoietin (containing 165 amino acids) could be identified with the aid of peptide libraries on phage surfaces (phage display). The crystal structure of a peptide dimer complexed with two erythropoietin receptors (shown on the right) pr