## Abstract A solvent‐free asymmetric and direct __anti__‐aldol reaction of aliphatic ketones with aromatic aldehydes catalyzed by recyclable L‐prolineamides and L‐prolinethioamides **3** is studied. The L‐prolinethioamide **3d** (5 mol%), derived from L‐Pro and (__R__)‐1‐aminoindane, is the most e
ChemInform Abstract: Prolinamides versus Prolinethioamides as Recyclable Catalysts in the Enantioselective Solvent-Free Inter- and Intramolecular Aldol Reactions.
✍ Scribed by Diana Almasi; Diego A. Alonso; Carmen Najera
- Publisher
- John Wiley and Sons
- Year
- 2009
- Weight
- 66 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract magnified image Organocatalysts **1**, derived from L‐proline and (1__S__,2__R__)‐__cis__‐1‐aminoindan‐2‐ol or (__R__)‐1‐aminoindane, are evaluated as promoters in the direct asymmetric aldol reaction between ketones and aromatic aldehydes in the presence of water and under solvent‐fre
## Abstract Polystyrene‐supported binam‐prolinamide (PSBP) is used as catalyst in the aldol reaction between several ketones and aldehydes under solvent‐free or aqueous conditions affording the corresponding aldol product in high regio‐, diastereo, and enantioselectivities.