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ChemInform Abstract: Preparation of Arylmercapturic Acids by S-Arylation of N,N′-Diacetylcystine.

✍ Scribed by Jan Krouzelka; Igor Linhart


Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
41
Category
Article
ISSN
0931-7597

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Preparation of Arylmercapturic Acids by
✍ Jan Krouželka; Igor Linhart 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 269 KB

A simple convenient method has been developed for the preparation of N-acetyl-S-arylcysteines based on the Chan-Lam-Evans arylation of N,NЈ-diacetylcystine dimethyl ester with arylboronic acids and used to synthesize a series of arylmercapturic acids. Unlike copper-mediated N-arylation, the