Preparation of Arylmercapturic Acids by
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Jan Krouželka; Igor Linhart
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Article
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2009
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John Wiley and Sons
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English
⚖ 269 KB
A simple convenient method has been developed for the preparation of N-acetyl-S-arylcysteines based on the Chan-Lam-Evans arylation of N,NЈ-diacetylcystine dimethyl ester with arylboronic acids and used to synthesize a series of arylmercapturic acids. Unlike copper-mediated N-arylation, the