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ChemInform Abstract: Preparation of 2,5-Disubstituted 2-Thiazolines.

โœ Scribed by V. V. KARPYAK; N. D. OBUSHAK; N. I. GANUSHCHAK

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
29
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Preparation of 2,5-Disubstituted 2-Thiazolines.

-A new synthetic access to the title thiazolines is presented. The isothiocyanates (I) and (VI), prepared by chloroarylation of allylisothiocyanate with aryldiazonium chlorides, undergo cyclization in the presence of bases to afford the target thiazolines in good yield.

๐Ÿ“œ SIMILAR VOLUMES

Halogenoarylation of allyl isothiocyanat
Halogenoarylation of allyl isothiocyanate: Synthesis of 2,5-disubstituted 2-thiazolines
โœ Mykola D. Obushak; Volodymyr V. Karpyak; Mykola I. Ganushchak ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 239 KB

A new approach to the synthesis of 2-R-5-benzyl-2-thiazolines with the use of chloro-and bromoarylation products of allyl isothiocyanate with arenediazonium halides was elaborated. The isothiocyanates obtained were reacted with ammonia, aliphatic or aromatic amines, and sodium methoxide. The use of