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ChemInform Abstract: Preparation and Use of Enantiomerically Pure α-Tetrasubstituted . alpha.-Amino Acids

✍ Scribed by B. KAPTEIN; W. H. J. BOESTEN; W. J. J. VAN DEN TWEEL; Q. B. BROXTERMAN; H. E. SCHOEMAKER; F. FORMAGGIO; M. CRISMA; C. TONIOLO; J. KAMPHUIS


Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
28
Category
Article
ISSN
0931-7597

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Preparation and Properties of Enantiomerically Pure N α -Tritylamino Acid Fluorides. -Acyl fluorides of type (II) and (XI), prepared by fluorination of amino acids with cyanuric fluoride (CNF), are powerful acylating agents for peptide synthesis. Their reactivity is further demonstrated by reaction