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ChemInform Abstract: Preparation and Atropisomerism of 1-[2-(2,2-Dimethylpiperidin-1-yl)phenyl]ethanol.

✍ Scribed by H. Moehrle; M. Jeandree

Publisher: John Wiley and Sons
Year: 2010
Weight: 27 KB
Volume: 32
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200131143

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Asymmetric Synthesis of Both Enantiomers of 2-(Dimethylamino)-1-[3-methoxy-2-(1-methylethoxy)phenyl]ethanol. -The synthesis of both enantiomers of the title compound (IX) based on the Sharpless asymmetric dihydroxylation of the vinylbenzene (IV) is described. Evaluation of their in vitro uroselecti