## Abstract A practical semiβsynthetic method of (__S__)β7β(2βisopropylamino)ethylcamptothecin hydrochloride has been developed. The Mannich reaction of (__S__)β7βmethylcamptothecin with isopropylamine hydrochloride in dimethyl sulfoxide as a formaldehyde source gave the desired product in moderate
β¦ LIBER β¦
ChemInform Abstract: Practical Synthesis of (S)-7-(2-Isopropylamino)ethylcamptothecin Hydrochloride, Potent Topoisomerase I Inhibitor.
β Scribed by Soon Kil Ahn; Nam Song Choi; Byeong Seon Jeong; Kye Kwang Kim; Duck Jin Journ; Joon Kyum Kim; Sang Joon Lee; Jung Woo Kim; Chung Il Hong; Sang-sup Jew
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 29 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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