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ChemInform Abstract: Potent Antiprotozoal Activity of a Novel Semi-Synthetic Berberine Derivative.

✍ Scribed by A. Douglas Kinghorn; et al. et al.

Publisher
John Wiley and Sons
Year
2012
Weight
11 KB
Volume
43
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

The semi‐synthetic berberine analogue (I) reveals nanomolar level potency against in vitro models of leishmaniasis, malaria, and trypanosomiasis, and shows activity in an in vivo visceral leishmaniasis model.

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